1-Tuple DNA sequencing: computer analysis.

  title={1-Tuple DNA sequencing: computer analysis.},
  author={Pavel A. Pevzner},
  journal={Journal of biomolecular structure & dynamics},
  volume={7 1},
A new method of DNA reading was proposed at the end of 1988 by Lysov et al. According to the authors' claims it has certain advantages as compared to the Maxam-Gilbert and Sanger methods, which are revealed by automation and rapidity of DNA sequencing. Nevertheless its employment is hampered by a number of biological and mathematical problems. The present study proposes an algorithm that allows to overcome the computational difficulties occurring in the course of the method during… CONTINUE READING
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