South African learners particularly in schools with limited resources have continuously underachieved in the gateway subjects like Mathematics and Science. The government has turned to modern technology to strengthen teaching and learning and to redress past inequalities in its schools. This intervention has made little or no progress despite the availability of Information and Communication Technologies (ICTs) in these institutions (PanAfrican Research Agenda, 20082011). The teachers in these schools are still in the phase of using ICTs to merely transmit subject content rather than utilise the technologies to enhance learning. The ICT in Education policy, (DoE, 2004) advocates the pedagogical integration of ICTs that promotes the development of higher-order thinking skills. Teachers in these schools need competence and innovativeness to maximise the potential of digital devices if their use will improve thinking skills that are a significant component in enhancing learner performance. This literature review attempts to provide better understanding on what quality ICT use in the classroom entails to facilitate the advancement of teaching and learning. The intention is to demystify misconceptions associated with pedagogical use of ICTs in schools that tend to be responsible for failure to achieve educational goals by teachers in not well-resourced schools. Experiences of other educational institutions, globally and locally will later be reviewed, to demonstrate how ICTs have been used to enhance learning. Key Concepts: Quality of ICT use for teaching and enhancement of learning.