1 Improved 31 P Saturation Transfer Approach for Imaging Cerebral ATP Metabolic Rates In Vivo

Abstract

INTRODUCTION The cerebral ATP metabolism plays a central role in neuroenergetics for supporting brain energy and function and it is regulated by the three-site chemically exchange system of Pi↔ATP↔PCr for maintaining a stable ATP content in the brain. Recent progress has demonstrated that the use of in vivo P MRS combined with magnetization saturation… (More)

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