1 Human Anti-macrophage Migration Inhibitory Factor ( Mif ) Antibodies Inhibit Growth of Human Prostate Cancer Cells in Vitro and in Vivo

@inproceedings{Hussain20131HA,
  title={1 Human Anti-macrophage Migration Inhibitory Factor ( Mif ) Antibodies Inhibit Growth of Human Prostate Cancer Cells in Vitro and in Vivo},
  author={Filza Hussain and Michael Freissmuth and Dirk Voelkel and Michael Thiele and Patrice Douillard and Gerhard Antoine and Patrick Thurner and Hartmut J. Ehrlich and Hans-Peter Schwarz and Friedrich Scheiflinger and Randolf J. Kerschbaumer},
  year={2013}
}
Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine, originally discovered for its eponymous effect and now known for pleiotropic biological properties in immunology and oncology. Circulating MIF levels are elevated in several types of human cancer including prostate cancer. MIF is released presumably by both, stromal and tumor cells and enhances malignant growth and metastasis by diverse mechanisms, such as stimulating tumor cell proliferation, suppressing apoptotic… CONTINUE READING