1 Global Analysis of SUMO-Binding Proteins Identifies SUMOylation as a Key Regulator of the INO 80 Chromatin Remodeling Complex

@inproceedings{Cox20171GA,
  title={1 Global Analysis of SUMO-Binding Proteins Identifies SUMOylation as a Key Regulator of the INO 80 Chromatin Remodeling Complex},
  author={Eric R Cox and Woochang Hwang and Ijeoma Uzoma and Jianfei Hu and Catherine M. Guzzo and Junseop Jeong and Michael J Matunis and Jiang Qian and Heng Zhu and Seth Blackshaw},
  year={2017}
}
SUMOylation is a critical regulator of a broad range of cellular processes, and is thought to do so in part by modulation of protein interaction. To comprehensively identify human proteins whose interaction is modulated by SUMOylation, we developed an in vitro binding assay using human proteome microarrays to identify targets of SUMO1 and SUMO2. We then… CONTINUE READING