1-Deoxy-D-xylulose 5-phosphate reductoisomerase: an overview.

@article{Proteau20041DeoxyDxylulose5R,
  title={1-Deoxy-D-xylulose 5-phosphate reductoisomerase: an overview.},
  author={Philip J Proteau},
  journal={Bioorganic chemistry},
  year={2004},
  volume={32 6},
  pages={483-93}
}
The methylerythritol phosphate pathway to isoprenoids, an alternate biosynthetic route present in many bacteria, algae, plants, and the malarial parasite Plasmodium falciparum, has become an attractive target for the development of new antimalarial and antibacterial compounds. The second enzyme in this pathway, 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR; EC 1.1.1.267), has been shown to be the molecular target for fosmidomycin, a promising antimalarial drug. This enzyme converts 1… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

A selection strategy in plant transformation based on antisense oligodeoxynucleotide inhibition.

The Plant journal : for cell and molecular biology • 2014
View 2 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…