1 Cytochrome P 450 3 a 4 - Catalyzed Testosterone 6 - Hydroxylation . Stereochemistry , Kinetic Deuterium Isotope Effects , and Rate - Limiting Steps

Abstract

Joel A. Krauser‡ and F. Peter Guengerich§ From the Department of Biochemistry and Center in Molecular Toxicology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146 Running title: Isotope Effects in P450 3A4 Testosterone Oxidation Address correspondence to: Prof. F. Peter Guengerich, Department of Biochemistry, Vanderbilt University School of Medicine, 638 Robinson Research Building, 23 and Pierce Avenues, Nashville, Tennessee 37232-0146, Tel. 615 322-2261; Fax. 615 322-3141; E-Mail: f.guengerich@vanderbilt.edu

2 Figures and Tables

Cite this paper

@inproceedings{Krauser20051CP, title={1 Cytochrome P 450 3 a 4 - Catalyzed Testosterone 6 - Hydroxylation . Stereochemistry , Kinetic Deuterium Isotope Effects , and Rate - Limiting Steps}, author={Joel A. Krauser and Peter Guengerich}, year={2005} }