1-Aryl-2-amino/hydrazino-4-phenyl-1,6-dihydro-1,3,5-triazine-6-thione and related thiocarbamides/thiosemicarbazides as antithyroidal agents.

@article{Prasad19931Aryl2aminohydrazino4phenyl16dihydr,
  title={1-Aryl-2-amino/hydrazino-4-phenyl-1,6-dihydro-1,3,5-triazine-6-thione and related thiocarbamides/thiosemicarbazides as antithyroidal agents.},
  author={R. L. N. Sai Prasad and Punit Kumar Srivastava},
  journal={Archiv der Pharmazie},
  year={1993},
  volume={326 12},
  pages={963-6}
}
Different 1-aryl-2-benzylmercapto-4-phenyl-1,6-dihydro-1,3,5-triazine-6- thiones have been synthesized by known methods. These triazines on treatment with ammonia/hydrazine hydrate afforded the corresponding 1-aryl-2-amino/hydrazino-4-phenyl-1,6-dihydro-1,3,5-triazine-6-thiones which on treatment with arylisothiocyanates afforded the related thiocarbamide/thiosemicarbazides. Some of these compounds show appreciable antithyroidal activity.