1 Aptamers Selected for Recognizing Amyloid 2 β-protein — A Case for Cautious Optimism 3

@inproceedings{Rahimi20181AS,
  title={1 Aptamers Selected for Recognizing Amyloid 2 β-protein — A Case for Cautious Optimism 3},
  author={Farid Rahimi},
  year={2018}
}
Aptamers are versatile oligonucleotide ligands used for molecular recognition of diverse 8 targets. However, application of aptamers to the field of amyloid β-protein (Aβ) has been limited 9 so far. Aβ is an intrinsically disordered protein that exists in a dynamic conformational 10 equilibrium, presenting time-dependent ensembles of short-lived, metastable structures and 11 assemblies that have been generally difficult to isolate and characterize. Moreover, despite 12 understanding of… CONTINUE READING

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