1 2 3 Functional analysis of Bacillus subtilis genes involved 4 in the biosynthesis of 4-thiouridine in tRNA 5

@inproceedings{Rajakovich2012123,
  title={1 2 3 Functional analysis of Bacillus subtilis genes involved 4 in the biosynthesis of 4-thiouridine in tRNA 5},
  author={Lauren J. Rajakovich and John Tomlinson and Patr{\'i}cia Clara Pereira dos Santos},
  year={2012}
}
19 ThiI has been identified as an essential enzyme involved in the biosynthesis of thiamine and the 20 tRNA thionucleoside modification, 4-thiouridine. In Escherichia coli and Salmonella enterica, 21 ThiI acts as a sulfurtransferase, receiving the sulfur donated from the cysteine desulfurase IscS 22 and transferring it to the target molecule or additional sulfur carrier proteins. However, in 23 Bacillus subtilis and most species from the Firmicute phylum, ThiI lacks the rhodanese domain 24 that… CONTINUE READING

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