1α,24‐Dihydroxyvitamin D3 (tacalcitol) is effective against Hailey–Hailey disease both in vivo and in vitro

@article{Aoki1998124DihydroxyvitaminD,
  title={1$\alpha$,24‐Dihydroxyvitamin D3 (tacalcitol) is effective against Hailey–Hailey disease both in vivo and in vitro},
  author={Aoki and Hashimoto and Koseki and Hozumi and Kondo},
  journal={British Journal of Dermatology},
  year={1998},
  volume={139}
}
  • Aoki, Hashimoto, Kondo
  • Published 1 November 1998
  • Medicine, Biology
  • British Journal of Dermatology
We report a case of Hailey–Hailey disease (HHD) in which 1α,24‐dihydroxyvitamin D3 (tacalcitol) was effective both clinically (in vivo) and in explant cultures (in vitro) of a skin lesion. The patient was a 65‐year‐old man with HHD lesions in the axillary and inguinal areas bilaterally. We applied ointment containing 1α,24‐dihydroxyvitamin D3 (tacalcitol), an analogue of active vitamin D3, to the lesions and assessed its clinical effectiveness. The HHD lesions in both groins disappeared after… 
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