1,4-cyclohexadiene-1-alanine (2,5-dihydrophenylalanine) a new inhibitor of phenylalanine for the rat and Leuconostoc dextranicum 8086.

  title={1,4-cyclohexadiene-1-alanine (2,5-dihydrophenylalanine) a new inhibitor of phenylalanine for the rat and Leuconostoc dextranicum 8086.},
  author={Mary Lou Snow and Christine Lauinger and C. Ressler},
  journal={The Journal of organic chemistry},
  volume={33 5},

Stoffwechselprodukte von Mikroorganismen

Summaryl-2,5-Dihydrophenylalanine has been isolated from cultures of two strains of Streptomyces. The antibiotic activity of this compound is antagonized by Phenylalanine and

Synthesis of cyclohexa-1,4-dienephosphonoyl dichlorides

1,4-Cyclohexadiene and similar hydrocarbons can be prepared via the Birch reduction of aromatic hydrocarbons with metals in liquid ammonia [3]. However, this approach is limitedly applicable in the

Anti-persistent mycobacterial inhibitors from Streptomycessp. H7763 targeting isocitrate lyase andmalate synthase in the glyoxylate shunt of Mycobacterium sp.

In the search for persistent TB Inhibitors from soil actinomycetes metabolites, a positive extract was obtained and the hits strain was identified and designated as Streptomyces sp.

Stoffwechselprodukte von Mikroorganismen

  • H. Diekmann
  • Chemistry, Biology
    Archiv für Mikrobiologie
  • 2004
Coprogen B was transformed into chlorcoprogen by substitution and iodocoprogen resulted from the latter after halogen exchange, and a rule for the naming of metabolites with hydroxamic acid functions is suggested.

Stoffwechselprodukte von Mikroorganismen

SummaryL-2,5-Dihydrophenylalanine inhibits the growth of E. coli K 12 in synthetic liquid media when added during the lag phase at a concentration of 5×10-5 M (8.35 γ/ml). The inhibition is reversed

Hydrolysis in Pharmaceutical Formulations

This literature review presents hydrolysis of active pharmaceutical ingredients as well as the effects on dosage form stability due to hydrolysis of excipients. Mechanisms and measurement methods are

1,4-Dihydro-l-phenylalanine-its synthesis and behavior in the phenylalanine ammonia-lyase reaction.

Kinetic measurements with phenylalanine ammonia-lyase showed that 1,4-dihydro-l-phenylalanines is no substrate but a moderately good competitive inhibitor of the enzymatic reaction, providing further evidence for the plausibility of the recently proposed mechanism of action of phenylAlanine ammonia -lyase.

L-2,5-dihydrophenylalanine, an inducer of cathepsin-dependent apoptosis in human promyelocytic leukemia cells (HL-60).

Results indicated that DHPA was an inducer of cathepsin-dependent apoptosis in HL-60 cells, and this apoptosis was demonstrated by morphological changes and biochemical analysis.

Ozonolysis of (cyclohexa-1,4-dienyl)-L-alanine. An approach to the synthesis of new unnatural amino acids. X-Ray molecular structure of 2-hydroxy-7-methyl-3-phenylpyrazolo[1,5-a]pyrimidine

The aromatic ring in L-phenylalanine was transformed into isoxazolyl, N-phenylpyrazolyl, and the bicyclic pyrazolo[1,5-a]pyrimidinyl groups, by a combination of Birch reduction and ozonolysis,