1,4-cyclohexadiene-1-alanine (2,5-dihydrophenylalanine) a new inhibitor of phenylalanine for the rat and Leuconostoc dextranicum 8086.
@article{Snow196814cyclohexadiene1alanineA, title={1,4-cyclohexadiene-1-alanine (2,5-dihydrophenylalanine) a new inhibitor of phenylalanine for the rat and Leuconostoc dextranicum 8086.}, author={Mary Lou Snow and Christine Lauinger and C. Ressler}, journal={The Journal of organic chemistry}, year={1968}, volume={33 5}, pages={ 1774-80 } }
39 Citations
Dihydrophenylalanine: a prephenate-derived Photorhabdus luminescens antibiotic and intermediate in dihydrostilbene biosynthesis.
- Biology, ChemistryChemistry & biology
- 2011
Stoffwechselprodukte von Mikroorganismen
- ChemistryArchiv für Mikrobiologie
- 2004
Summaryl-2,5-Dihydrophenylalanine has been isolated from cultures of two strains of Streptomyces. The antibiotic activity of this compound is antagonized by Phenylalanine and…
Synthesis of cyclohexa-1,4-dienephosphonoyl dichlorides
- ChemistryRussian Journal of General Chemistry
- 2013
1,4-Cyclohexadiene and similar hydrocarbons can be prepared via the Birch reduction of aromatic hydrocarbons with metals in liquid ammonia [3]. However, this approach is limitedly applicable in the…
Anti-persistent mycobacterial inhibitors from Streptomycessp. H7763 targeting isocitrate lyase andmalate synthase in the glyoxylate shunt of Mycobacterium sp.
- Biology, Chemistry
- 2012
In the search for persistent TB Inhibitors from soil actinomycetes metabolites, a positive extract was obtained and the hits strain was identified and designated as Streptomyces sp.
Stoffwechselprodukte von Mikroorganismen
- Chemistry, BiologyArchiv für Mikrobiologie
- 2004
Coprogen B was transformed into chlorcoprogen by substitution and iodocoprogen resulted from the latter after halogen exchange, and a rule for the naming of metabolites with hydroxamic acid functions is suggested.
Stoffwechselprodukte von Mikroorganismen
- ChemistryArchiv für Mikrobiologie
- 2004
SummaryL-2,5-Dihydrophenylalanine inhibits the growth of E. coli K 12 in synthetic liquid media when added during the lag phase at a concentration of 5×10-5 M (8.35 γ/ml). The inhibition is reversed…
Hydrolysis in Pharmaceutical Formulations
- BiologyPharmaceutical development and technology
- 2002
This literature review presents hydrolysis of active pharmaceutical ingredients as well as the effects on dosage form stability due to hydrolysis of excipients. Mechanisms and measurement methods are…
1,4-Dihydro-l-phenylalanine-its synthesis and behavior in the phenylalanine ammonia-lyase reaction.
- Chemistry, BiologyArchives of biochemistry and biophysics
- 2001
Kinetic measurements with phenylalanine ammonia-lyase showed that 1,4-dihydro-l-phenylalanines is no substrate but a moderately good competitive inhibitor of the enzymatic reaction, providing further evidence for the plausibility of the recently proposed mechanism of action of phenylAlanine ammonia -lyase.
L-2,5-dihydrophenylalanine, an inducer of cathepsin-dependent apoptosis in human promyelocytic leukemia cells (HL-60).
- Biology, ChemistryThe Journal of antibiotics
- 2001
Results indicated that DHPA was an inducer of cathepsin-dependent apoptosis in HL-60 cells, and this apoptosis was demonstrated by morphological changes and biochemical analysis.
Ozonolysis of (cyclohexa-1,4-dienyl)-L-alanine. An approach to the synthesis of new unnatural amino acids. X-Ray molecular structure of 2-hydroxy-7-methyl-3-phenylpyrazolo[1,5-a]pyrimidine
- Chemistry
- 1995
The aromatic ring in L-phenylalanine was transformed into isoxazolyl, N-phenylpyrazolyl, and the bicyclic pyrazolo[1,5-a]pyrimidinyl groups, by a combination of Birch reduction and ozonolysis,…