1,25-Dihydroxyvitamin D Levels in Pediatric Intensive Care Units: Risk Factors and Association With Clinical Course.

@article{Mcnally2015125DihydroxyvitaminDL,
  title={1,25-Dihydroxyvitamin D Levels in Pediatric Intensive Care Units: Risk Factors and Association With Clinical Course.},
  author={James Dayre Mcnally and Kusum Menon and M. L. Lawson and Kathryn A P Williams and Dermot R. Doherty},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2015},
  volume={100 8},
  pages={2942-5}
}
CONTEXT Multiple adult and some pediatric critical care studies have suggested that poor vitamin D status is associated with illness severity and outcome. The majority have evaluated vitamin D status through serum 25-hydroxyvitamin D [25(OH)D]. Critical illness-related organ dysfunction may result in impaired conversion of 25(OH)D to the active hormone 1,25-dihydroxyvitamin D [1,25(OH)2D]. Consequently 1,25(OH)2D levels could be an independent additive prognostic marker in the intensive care… CONTINUE READING