1,25-Dihydroxyvitamin D(3), phospholipase D and protein kinase C in keratinocyte differentiation.

  title={1,25-Dihydroxyvitamin D(3), phospholipase D and protein kinase C in keratinocyte differentiation.},
  author={Wendy Bollinger Bollag and Roni J. Bollag},
  journal={Molecular and cellular endocrinology},
  volume={177 1-2},
1,25-Dihydroxyvitamin D(3), thought to be a physiological regulator of epidermal keratinocyte growth and differentiation, also elicits the complete differentiative program in vitro, with expression of various genes/proteins characteristic of both early and late differentiation. 1,25-Dihydroxyvitamin D(3) functions by interacting with an intracellular receptor that binds to DNA at vitamin D response elements (VDRE) thereby affecting transcription. 1,25-Dihydroxyvitamin D(3) has been demonstrated… CONTINUE READING

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