1, 1, 1, 2 TETRAFLUOROETHANE: an inhalation anesthetic agent of intermediate potency

@article{Shulman1967111,
  title={1, 1, 1, 2 TETRAFLUOROETHANE: an inhalation anesthetic agent of intermediate potency},
  author={M. Shulman and M. Sadove},
  journal={Anesthesia & Analgesia},
  year={1967},
  volume={47},
  pages={629–635}
}
URLNG the past two decades, extensive D investigations have been conducted on fluorocarbons in an attempt to find new and useful inhalation anesthetic agents.1-3 Of the several directions these investigations have taken, one of the most interesting has been the search for agents of intermediate potency. This concept was originally advanced by Artusio and Van Poznak4-6 and served as the basis of a series of extensive investigations by them. 
21 Citations

Figures, Tables, and Topics from this paper

Defluorination of 1,1,1,2-tetrafluoroethane (R-134a) by rat hepatocytes.
R-134a (1,1,1,2-Tetrafluoroethane) Inhalation Induced Reactive Airways Dysfunction Syndrome
Anaesthetic in the garb of a propellant
The development of environmentally acceptable fluorocarbons
  • G. Rusch
  • Biology, Medicine
  • Critical reviews in toxicology
  • 2018
An anesthetic in use with bronchodilator inhaler: a fact less known.
Evaluating Chemical and other Agent Exosures for Reproductive and Developmental Toxicity
The Manhattan Legacy
...
1
2
3
...

References

SHOWING 1-7 OF 7 REFERENCES
Safety Evaluation and Anesthetic Properties of l,l,l-Trifluoroethyl Chloride
  • Toxicol. Appl. Pharmacol
  • 1965
The action of fluothane; a new volatile anaesthetic.
  • J. Raventós
  • Medicine, Chemistry
  • British journal of pharmacology and chemotherapy
  • 1956
Preliminary studies of the anesthetic activity of fluorinated hydrocarbons.
  • B. Robbins
  • Chemistry, Medicine
  • The Journal of pharmacology and experimental therapeutics
  • 1946