0688 - MITOGENIC EFFECT OF BISPHOSPHONATES ON OSTEOBLASTIC CELLS

@inproceedings{20000688M,
  title={0688 - MITOGENIC EFFECT OF BISPHOSPHONATES ON OSTEOBLASTIC CELLS},
  author={},
  year={2000}
}
  • Published 2000
Introduction Bisphosphonates are a family of analogous synthetic pyrophosphates, which are effective inhibitors of bone resorption and are approved by the FDA to treat bone loss associated with osteoporosis and Paget’s disease. We have previously demonstrated that alendronate, a 2 generation bisphosphonate, can effectively inhibit wear debris mediated osteolysis in a canine model. Based on these convincing findings, the efficacy of alendronate in treating osteolysis is currently being evaluated… CONTINUE READING

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