0377 : Phosphoinositide 3-kinase gamma: a potential clinical target in the prevention of vascular damages inuced by arterial injury

@inproceedings{Lupieri20150377P,
  title={0377 : Phosphoinositide 3-kinase gamma: a potential clinical target in the prevention of vascular damages inuced by arterial injury},
  author={Adrien Lupieri and Natalia F Smirnova and Gervaise Loirand and Jean-François Arnal and Nathalie Vailland and Nicole Malet and Matthias P Wymann and Emilio Hirsch and Alain-Pierre Gadeau and Laurent O. Martinez and Abdelhadi Saoudi and St{\'e}phanie Gayral and Muriel Laffargue},
  year={2015}
}
Context Angioplasty with stent placement, used to treat symptomatic atherosclerosis plaques, is frequently complicated by restenosis. This pathology is characteried by fibroproliferative and immuno-inflammatory mechanisms of the arterial wall, called intimal hyperplasia (IH). Aims Our previous results demonstrated that phosphoinositide 3-kinase (??(PI3K(??) was a key mediator of inflammatory processes of the arterial wall leading to atherosclerosis. We now proposed this enzyme as a potential… CONTINUE READING