0.3% Tacrolimus gel and 0.5% Tacrolimus cream show efficacy in mild to moderate plaque psoriasis: Results of a randomized, open-label, observer-blinded study.

@article{Ortonne200603TG,
  title={0.3% Tacrolimus gel and 0.5% Tacrolimus cream show efficacy in mild to moderate plaque psoriasis: Results of a randomized, open-label, observer-blinded study.},
  author={Jean-paul Ortonne and Peter Cornelius Maria van de Kerkhof and Joerg Christoph Prinz and Thomas Bieber and Morad Lahfa and Andris Rubins and Gottfried Wozel and G{\'e}rard Lorette},
  journal={Acta dermato-venereologica},
  year={2006},
  volume={86 1},
  pages={29-33}
}
The efficacy and safety of 0.3% tacrolimus gel and 0.5% tacrolimus cream compared with calcipotriol ointment were evaluated in adults (n = 124) with mild to moderate plaque psoriasis. Treatment was twice daily for a maximum of 12 weeks. Clinical efficacy was assessed by the percentage change in the local psoriasis severity index of a target lesion between baseline and week 12. By week 12, the median percentage changes in local psoriasis severity index of the target lesions in the tacrolimus gel… CONTINUE READING