Negative pressure wound therapy-associated tissue trauma and pain: a controlled in vivo study comparing foam and gauze dressing removal by immunohistochemistry for substance P and calcitonin gene-related peptide in the wound edge.

@article{Malmsj2011,
  title={Negative pressure wound therapy-associated tissue trauma and pain: a controlled in vivo study comparing foam and gauze dressing removal by immunohistochemistry for substance P and calcitonin gene-related peptide in the wound edge.},
  author={Malin Malmsj{\"o} and Lotta Gustafsson and Sandra Lindstedt and Richard Ingemansson},
  journal={Ostomy/wound management},
  year={2011},
  volume={57 12},
  pages={
          30-5
        }
}
Pain upon negative pressure wound therapy (NPWT) dressing removal has been reported and is believed to be associated with the observation that granulation tissue grows into foam. Wound tissue damage upon removal of the foam may cause the reported pain. Calcitonin gene-related peptide (CGRP) and substance P are neuropeptides that cause inflammation and signal pain and are known to be released when tissue trauma occurs. The aim of this controlled in vivo study was to compare the expression of… CONTINUE READING

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 10 CITATIONS

Pain and trauma in negative pressure wound therapy: a review.

  • International wound journal
  • 2015
VIEW 5 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 21 REFERENCES

Similar biological effects of green and black polyurethane foam in negative pressure wound therapy: green foam facilitates monitoring of wound status, bleeding and exudate

M Malmsjo, R. Ingemansson
  • 20th Conference of the European Wound Management Association. Geneva, Switzerland. May 26–28,
  • 2010

Comparison of Foam and Gauze Based Negative Pressure Wound Therapy on the Healing of Open Wounds in Dogs

MG Demaria, BJ Stanley, JG Hauptman
  • Poster presentation at Clinical Symposium on Advances in Skin & Wound
  • 2009