„Natural”︁ killer cells in the mouse. II. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Characteristics of the killer cell

@article{Kiessling1975NaturalKC,
  title={„Natural”︁ killer cells in the mouse. II. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Characteristics of the killer cell},
  author={R. Kiessling and Eva Klein and H. Pross and H. Wigzell},
  journal={European Journal of Immunology},
  year={1975},
  volume={5}
}
  • R. Kiessling, Eva Klein, +1 author H. Wigzell
  • Published 1975
  • Biology, Medicine
  • European Journal of Immunology
  • Normal mice contain cytolytic cells with specificity for in vitro grown mouse Moloney leukemia cells. Such killer cells are most frequent in the spleens; lymph node and bone marrow contain less and thymus virtually no killer activity. Peak activity is found around one to three months of age. Spleen cells from genetically athymic mice are as active killer cells as those from normal mice of the same strain. Treatment with anti‐theta serum plus complement followed by removal of adherent and… CONTINUE READING
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