“You Shall Not Pass”—tight junctions of the blood brain barrier

  title={“You Shall Not Pass”—tight junctions of the blood brain barrier},
  author={H. C Bauer and Istv{\'a}n Krizbai and Hannelore Bauer and Andreas Traweger},
  booktitle={Front. Neurosci.},
The structure and function of the barrier layers restricting the free diffusion of substances between the central nervous system (brain and spinal cord) and the systemic circulation is of great medical interest as various pathological conditions often lead to their impairment. Excessive leakage of blood-borne molecules into the parenchyma and the concomitant fluctuations in the microenvironment following a transient breakdown of the blood-brain barrier (BBB) during ischemic/hypoxic conditions… CONTINUE READING
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