“The study of the association between genotype and phenotypic manifestations of the Huntington’s chorea pathogenesis”

@article{Gryshchenko2009TheSO,
  title={“The study of the association between genotype and phenotypic manifestations of the Huntington’s chorea pathogenesis”},
  author={N. V. Gryshchenko and A. M. Kucherenko and E. I. Patscun and Liudmyla A Livshits},
  journal={Cytology and Genetics},
  year={2009},
  volume={43},
  pages={183-187}
}
Direct molecular-genetic analysis of the region containing CAG and CCG repeats of the IT15 gene from 37 patients with the clinical diagnosis of Huntington’s chorea was carried out. The allele with the expansion of CAG repeats in the state of heterozygosity was found in 33 patients; DNA analysis did not confirm a clinical diagnosis in four cases. Twenty… CONTINUE READING