“Physiological and Morphological Characterization of Genetically Defined Classes of Interneurons in Respiratory Rhythm and Pattern Generation of Neonatal Mice”

Abstract

Breathing in mammals depends on an inspiratory-related rhythm that is generated by glutamatergic neurons in the preBötzinger complex (preBötC), a specialized site of the lower brainstem. Rhythm-generating preBötC neurons are derived from a single lineage that expresses the transcription factor (TF) Dbx1, but the cellular mechanisms of rhythmogenesis remain… (More)

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