“Field cancerization” in oral stratified squamous epithelium. Clinical implications of multicentric origin

@article{Slaughter1953FieldCI,
  title={“Field cancerization” in oral stratified squamous epithelium. Clinical implications of multicentric origin},
  author={Danely P. Slaughter and Harry W. Southwick and Walter Smejkal},
  journal={Cancer},
  year={1953},
  volume={6}
}
Oral Hybrid Verrucous Carcinoma: A Clinical Study
TLDR
Tumour staging is often unreliable in predicting prognosis of hybrid VC, occurrence of second primary oral cancer and recurrence appears to be significant factors effecting prognosis.
Angular domain imaging in scattering media with background subtraction, multi-spectral sources, and fluorescence
.......................................................................................................................................... iii Acknowledgements
Effects of Human Oral Mucosal Tissue, Saliva, and Oral Microflora on Intraoral Metabolism and Bioactivation of Black Raspberry Anthocyanins
TLDR
Data show that comparable to the small intestine, the requisite hydrolytic, phase II and efflux transporting enzymes necessary for local enteric recycling are present and functional in human oral mucosa.
The Value of Virtual Chromoendoscopy in the Workup of Patients with Head and Neck Squamous Cell Carcinoma
TLDR
Countering these drawbacks, NBI shows a high potential in early ESPT detection in high-risk patients, and additional multicenter studies are needed to compare diagnostic performance and cost-effectiveness of NBI and other VCE techniques with LCE.
Screening for head and neck second primary tumors in patients with esophageal squamous cell cancer: A systematic review and meta-analysis
TLDR
Based on the results, HNSPT screening could be considered in patients with primary ESCC, and it is not clear whether this consideration applies to the Western world.
Danely P.Slaughters Field Cancerization Concept of Carcinogenesis: The Path Forward to Early Cancer Detection and Chemoprevention
TLDR
With current technological advancements, biomarkers of field cancerization can be assayed using even noninvasive samples such as body fluids such as saliva and bronchial washes and should enable risk stratification, and hence close surveillance of individuals at risk for early cancer detection or the early deployment of chemopreventive strategies.
The efficacy of a photolyase-based device on the cancerization field: a clinical and thermographic study
TLDR
Whether HHs have the same histological or immunohistochemical characteristics as the CF is verified and the results indicate that ATT could represent a useful paraclinic method in identifying CFs in subjects at risk.
Oral second primary tumour risk predictors : clinical factors and loss of heterozygosity
................................................................................................................................... ii Preface
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