• Corpus ID: 4492671

“ Evaluation of Study Designs In Anti-Tubercular Regimen ” – A Review

@inproceedings{Sara2017EO,
  title={“ Evaluation of Study Designs In Anti-Tubercular Regimen ” – A Review},
  author={Khan Sara and G. Anusha and M. Sahithi and Dasari Tejaswini and Krishna Teja and K. Hari Prasath},
  year={2017}
}
Anti-tubercular drugs used in clinical practice, are not free from ADRs. The added problem is that combinations of drugs are always used for prolonged periods of time therefore; it is likely that the adverse reactions of one drug may be potentiated by the companion drugs used. Moreover, the Adverse Drug Reactions (ADRs) to the drugs used is one of the major reasons for the patient default treatment. Anti-tubercular drugs may result in ADRs involving almost all system in body, including the… 

References

SHOWING 1-10 OF 23 REFERENCES

ADVERSE DRUG REACTIONS ASSOCIATED WITH FIRST-LINE ANTI TUBERCULAR DRUGS IN A TERTIARY CARE HOSPITAL OF CENTRAL INDIA: A STUDY OF CLINICAL PRESENTATIONS, CAUSALITY, AND SEVERITY

TLDR
Vigilance regarding these ADRs occurrences can result in early diagnosis and thus, proper management can be instituted earliest, and this will build confidence of patients and will decrease the dropouts which in turn will result in decrease chances of developing drug-resistant strains.

Profile of adverse drug reactions in patients on anti-tubercular drugs in a sub Himalayan rural tertiary care teaching hospital -

TLDR
ADRs involving different organ systems were seen in both categories with varied frequency and add to hospitalization expenses, insurance costs and increase in work loss days besides addition to patient suffering and loss of compliance.

A Prospective, Observational Study of Adverse Reactions to Drug Regimen for Multi-Drug Resistant Pulmonary Tuberculosis in Central India

TLDR
ADRs were common in patients of MDR-TB on DOTs-Plus drug regimen compared to DOTS regimen in non-resistant TB and was due to lack of availability of safer and equally potent drugs in DOTs/DOTS drug regimen.

Adverse Drug Reaction Profile in Patients on Anti-tubercular Treatment Alone and in Combination with Highly Active Antiretroviral Therapy.

TLDR
It is underscores that concomitant HAART and ATT, result in more ADRs in comparison to ATT alone demanding collaboration & integration of National AIDS Control programme and PvPI to enhance drug safety in this field.

A Study of Anti-Tubercular Drug Induced Adverse Reactions in Patients Attending Pulmonary Medicine Department of a Tertiary Care Teaching Hospital

TLDR
Patients attending to Pulmonary Medicine department at I.M.S. & SUM Hospital, a tertiary care teaching hospital in eastern India, receiving Anti-TB drugs for at least eight months were included in study and the incidence & pattern of ADRs caused by anti tubercular drugs were identified and the causality & severity of the reported ADRs were assessed.

Adverse Reactions to Antituberculosis Drugs in Iranian Tuberculosis Patients

TLDR
It was found that severe side effects of anti-TB drugs are common in patients who have risk factors of ADRs and they should be followed up by close monitoring.

Evaluation of anti-tuberculosis induced adverse reactions in hospitalized patients

TLDR
Anti-TB drugs could cause significant adverse effects both in quantity and severity leading to hospitalization, prolonged hospital stay and even death, so more attention is needed to prevent these reactions.

Adverse Reactions Due to Directly Observed Treatment Strategy Therapy in Chinese Tuberculosis Patients: A Prospective Study

TLDR
The importance of developing strategies to ameliorate adverse drug reactions due to DOTS therapy both to improve the quality of patient care and to control TB safely is highlighted.

A study on adverse drug reactions to first line antitubercular drugs in DOTS therapy

TLDR
It is estimated that annually around 330,000 Indians die due to TB, and in India, nearly 2 million people develop active disease every year and about 0.5 million die from it.

Design of the Anti-tuberculosis Drugs induced Adverse Reactions in China National Tuberculosis Prevention and Control Scheme Study (ADACS)

TLDR
The ADACS will give an overview of anti-TB drugs induced ADRs' incidences, risk factors, treatments, prognoses, and clinical, economical and public health impacts for TB patients applying CNTS regimen in China, and provide suggestions for individualized health care and TB control policy.