‘Puppet’ Children A Report on Three Cases

@article{Angelman1965PuppetCA,
  title={‘Puppet’ Children A Report on Three Cases},
  author={Harry Angelman},
  journal={Developmental Medicine \& Child Neurology},
  year={1965},
  volume={7}
}
  • H. Angelman
  • Published 1 December 1965
  • Medicine
  • Developmental Medicine & Child Neurology
Three unrelated children are described with similar physical abnormalities of congenital origin, reminiscent of puppet children, and profound mental retardation. 
Three More ‘Happy Puppets’
TLDR
Three children with mental and physical retardation and with other features compatible with Angelman's ‘happy puppet’ syndrome are presented and it seems likely that this syndrome is a definite clinical entity, although the aetiology is still unknown.
The Angelman (Happy Puppet) syndrome: is it autosomal recessive?
TLDR
Seven cases of Angelman's syndrome from three families are reported, and recurrence risks are not small, as previously suggested.
Angelman syndrome in an infant boy
TLDR
The patient's mother was concerned about his flat head and preference for turning his head to the right, which led to a referral and eventual correct diagnosis of Angelman syndrome.
‘Puppet’ children. A report on three cases (1965)
  • H. Hart
  • Medicine
    Developmental medicine and child neurology
  • 2008
TLDR
It will be seen that all these children possess a number of characteristic features in common and may be summarised as follows: flat heads, jerky movements, protruding tongues and bouts of laughter.
Angelman (“happy puppet”) syndrome —seven new cases documented by cerebral computed tomography: review of the literature
TLDR
It is concluded that diagnosis is difficult in the first years of life in children with Angelman syndrome.
A Survey of Expressive Communication Skills in Children With Angelman Syndrome
Angelman syndrome (AS) results from partial deletion of the 15th chromosome (Knoll et al., 1989) and occurs in approximately 1 per 10,000 live births (Petersen, Brondum-Nielsen, Hansen, & Wulff, 19...
The puppet-like syndrome of Angelman.
Five new cases are presented of a syndrome characterized mainly by severe mental retardation, epilepsy, puppet-like ataxic movements, microbrachycephaly, prognathism, tongue protrusion, and
The “happy puppet” syndrome in two siblings
TLDR
The occurrence of the “happy puppet” syndrome in the two siblings suggests a genetic etiology possibly as an autosomal recessive trait.
Recurrence risk in the Angelman ("happy puppet") syndrome.
TLDR
A review of the literature shows a low but not negligible recurrence risk of Angelman "happy puppet" syndrome, and different explanations for this are discussed.
Angelman (happy puppet) syndrome in a girl and her brother.
TLDR
The possible effect of voluntary restriction of family size after the birth of an affected child is discussed in relation to the possibility of autosomal recessive inheritance, but a recurrence risk of 5% is appropriate for use in the genetic clinic.
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