‘Negativity bias’ in risk for depression and anxiety: Brain–body fear circuitry correlates, 5-HTT-LPR and early life stress

@article{Williams2009NegativityBI,
  title={‘Negativity bias’ in risk for depression and anxiety: Brain–body fear circuitry correlates, 5-HTT-LPR and early life stress},
  author={Leanne M. Williams and Justine M. Gatt and Peter R. Schofield and Gloria Olivieri and Anthony Peduto and Evian Gordon},
  journal={NeuroImage},
  year={2009},
  volume={47},
  pages={804-814}
}
The INTEGRATE Model draws on the framework of 'integrative neuroscience' to bring together brain-body and behavioral concepts of emotion, thinking and feeling and their regulation. The key organizing principle is the drive to 'minimize danger and maximize reward' that determines what is significant to us at each point in time. Traits of 'negativity bias' reflect the tendency to perceive danger rather than reward related information, and this bias influences emotion, thinking and feeling… CONTINUE READING
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