Молекулярные и клеточные механизмы воспаления при подагре: Molecular and cell mechanisms of inflammation in gout

@inproceedings{Malyshev2019,
  title={Молекулярные и клеточные механизмы воспаления при подагре: Molecular and cell mechanisms of inflammation in gout},
  author={I. Yu. Malyshev and A. E. Pihlak and O. P. Budanova},
  year={2019}
}
The review analyzes mechanisms of gouty inflammation and resolution of acute inflammation in gout and shows how their understanding contributes to creation of new technologies for the treatment of gout. The first part of the review addresses crystal-induced inflammation in gout, which is associated with activation of the NLRP3 inflammasome in macrophages. The crystal-induced inflammation consists of two stages, 1) synthesis of inflammasome components and 2) inflammasome assembly. The review… 

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