ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy.

@article{ORourke20136PF,
  title={ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy.},
  author={Eyleen J. O'Rourke and Petric Kuballa and Ramnik Xavier and Gary Ruvkun},
  journal={Genes & development},
  year={2013},
  volume={27 4},
  pages={429-40}
}
Adaptation to nutrient scarcity depends on the activation of metabolic programs to efficiently use internal reserves of energy. Activation of these programs in abundant food regimens can extend life span. However, the common molecular and metabolic changes that promote adaptation to nutritional stress and extend life span are mostly unknown. Here we present a response to fasting, enrichment of ω-6 polyunsaturated fatty acids (PUFAs), which promotes starvation resistance and extends… CONTINUE READING
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