ω-3 polyunsaturated fatty acids inhibit the proliferation of the lung adenocarcinoma cell line A549 in vitro.

@article{Yao20143PF,
  title={ω-3 polyunsaturated fatty acids inhibit the proliferation of the lung adenocarcinoma cell line A549 in vitro.},
  author={Qing-hua Yao and Xiao-chen Zhang and Ting Fu and Jian-zhong Gu and Lu Wang and Yun Wang and Yue-Biao Lai and Yu-qi Wang and Yong Guo},
  journal={Molecular medicine reports},
  year={2014},
  volume={9 2},
  pages={401-6}
}
ω-3 polyunsaturated fatty acids (n-3 PUFA), in particular the marine-derived forms eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been demonstrated to affect cancer cell replication, the cell cycle and cell death. Epidemiological studies have also suggested diets rich in n-3 PUFA were inversely correlated with the development of cancer. In the present study, we explored the effects of DHA and EPA on the proliferation activity and apoptosis of the human lung adenocarcinoma cell… CONTINUE READING

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