μPAD Fluorescence Scattering Immunoagglutination Assay for Cancer Biomarkers from Blood and Serum.

@article{Baynes2018PADFS,
  title={μPAD Fluorescence Scattering Immunoagglutination Assay for Cancer Biomarkers from Blood and Serum.},
  author={Cayla Baynes and Jeong-Yeol Yoon},
  journal={SLAS technology},
  year={2018},
  volume={23 1},
  pages={
          30-43
        }
}
A microfluidic paper analytical device (μPAD) was created for the sensitive quantification of cancer antigens, carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA 19-9), from human whole blood and serum, toward diagnosis and prognosis of colorectal cancer. Anti-CEA and anti-CA 19-9 antibodies were covalently linked to submicron, fluorescent polystyrene particles, loaded, and then dried in the center of the μPAD channel. CEA- or CA 19-9-spiked blood or serum samples were loaded to… CONTINUE READING
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