κ-opioid receptor as a key mediator in the regulation of appetitive 50-kHz ultrasonic vocalizations

@article{Hamed2014opioidRA,
  title={κ-opioid receptor as a key mediator in the regulation of appetitive 50-kHz ultrasonic vocalizations},
  author={Adam Hamed and Janusz Szyndler and Ewa Taracha and Danuta Turzyńska and Alicja Sobolewska and Małgorzata H Lehner and Paweł Krząścik and Patrycja Daszczuk},
  journal={Psychopharmacology},
  year={2014},
  volume={232},
  pages={1941-1955}
}
Acute administration of high doses of morphine reduced 50-kHz ultrasonic vocalizations (USVs). Although morphine meets the classical criteria for inducing 50-kHz USVs (it causes place preference and induces dopamine release in nucleus accumbens), it also inhibits appetitive vocalizations. The aims of this study were to (i) study the pharmacological impact of κ-opioid (KOR) and μ-opioid receptor (MOR) ligands on the emission of 50-kHz USVs triggered by social interaction after long-term… CONTINUE READING

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