γ-heregulin is the product of a chromosomal translocation fusing the DOC4 and HGL/NRG1 genes in the MDA-MB-175 breast cancer cell line

Abstract

γ-heregulin is a recently described novel isoform of the heregulin/neuregulin class of EGF-like ligands that bind to and activate receptors of the ErbB family. Deregulated signaling through the heregulin-ErbB pathway is thought to be implicated in the development of a subset of human breast cancers. γ-heregulin has been found to be expressed in the culture… (More)
DOI: 10.1038/sj.onc.1202950

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@article{Wang1999heregulinIT, title={γ-heregulin is the product of a chromosomal translocation fusing the DOC4 and HGL/NRG1 genes in the MDA-MB-175 breast cancer cell line}, author={Xiao Z. Wang and Ethel M.C. Jolicoeur and Nathalie Conte and Max Chaffanet and YuHong Zhang and Marie-Jo{\"e}lle Mozziconacci and Helen Feiner and Daniel Birnbaum and M. J. P{\'e}busque and David S{\'a}nchez de Ron}, journal={Oncogene}, year={1999}, volume={18}, pages={5718-5721} }