γ-Hydroxybutyric acid induces oxidative stress in cerebral cortex of young rats
@article{Sgaravatti2007HydroxybutyricAI, title={γ-Hydroxybutyric acid induces oxidative stress in cerebral cortex of young rats}, author={{\^A}. M. Sgaravatti and M. B. Sgarbi and C. G. Testa and K. Durigon and C. Dutra-Filho}, journal={Neurochemistry International}, year={2007}, volume={50}, pages={564-570} }
GHB is a naturally occurring compound in the central nervous system (CNS) whose tissue concentration are highly increased during drug abuse and in the inherited deficiency of succinic semialdehyde dehydrogenase (SSADH) activity. SSADH deficiency is a neurometabolic-inherited disorder of the degradation pathway of gamma-aminobutyric acid (GABA). It is biochemically characterized by increased concentrations of gamma-hydroxybutyric acid (GHB) in tissues, cerebrospinal fluid (CSF), blood and urine… CONTINUE READING
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