γ-Guanidinobutyric Acid as a Convulsive Substance

@article{Jinnai1966GuanidinobutyricAA,
  title={γ-Guanidinobutyric Acid as a Convulsive Substance},
  author={Dennosuke Jinnai and A Sawai and Akitane Mori},
  journal={Nature},
  year={1966},
  volume={212},
  pages={617-617}
}
IRREVERKE et al.1,2 have demonstrated the presence of γ-guanidinobutyric acid in the brain, kidney and liver of animals, using paper chromatography, and have isolated the substance in pure form from calf brain. Pisano, Mitoma and Udenfriend3 demonstrated that γ-guanidino-butyric acid is produced from y-aminobutyric acid and arginine by transamidinase activity in mammalian kidney. The present communication describes the seizures caused by administration of the compound to rabbits.