γ‐Glutamylcysteine ethyl ester protection of proteins from Aβ(1–42)‐mediated oxidative stress in neuronal cell culture: A proteomics approach

@article{BoydKimball2005GlutamylcysteineEE,
  title={$\gamma$‐Glutamylcysteine ethyl ester protection of proteins from A$\beta$(1–42)‐mediated oxidative stress in neuronal cell culture: A proteomics approach},
  author={Debra Boyd-Kimball and Rukhsana Sultana and H. Fai Poon and Hafiz Mohmmad-Abdul and Bert C. Lynn and Jon B. Klein and David Allan Butterfield},
  journal={Journal of Neuroscience Research},
  year={2005},
  volume={79}
}
Protein oxidation mediated by amyloid β‐peptide (1–42) (Aβ[1–42]) has been proposed to play a central role in the pathogenesis of Alzheimer's disease (AD), a neurodegenerative disorder associated with aging and the loss of cognitive function. The specific mechanism by which Aβ(1–42), the primary component of the senile plaque and a pathologic hallmark of AD, contributes to the oxidative damage evident in AD brain is unknown. Moreover, the specific proteins that are vulnerable to oxidative… 
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