β3GnT8 regulates laryngeal carcinoma cell proliferation via targeting MMPs/TIMPs and TGF-β1.

Previous evidence showed β1, 3-N-acetylglucosaminyltransferase 8 (β3GnT8), which can extend polylactosamine on N-glycans, to be highly expressed in some cancer cell lines and tissues, indicating roles in tumorigenesis. However, so far, the function of β3GnT8 in laryngeal carcinoma has not been characterized. To test any contribution, Hep-2 cells were stably… CONTINUE READING