β2‐Adrenergic Receptor Gene Variations Associated with Stage‐2 Hypertension in Northern Han Chinese

@article{Ge20052AdrenergicRG,
  title={$\beta$2‐Adrenergic Receptor Gene Variations Associated with Stage‐2 Hypertension in Northern Han Chinese},
  author={D. Ge and J. Huang and J. He and B. Li and X. Duan and R. Chen and D. Gu},
  journal={Annals of Human Genetics},
  year={2005},
  volume={69}
}
The aim of this study was to investigate the association between polymorphisms in the β2‐adrenergic receptor gene (ADRB2) (−47C/T, Arg16/Gly, Gln27/Glu) and stage‐2 hypertension in northern Han Chinese. We recruited 503 individuals with stage‐2 hypertension and 504 age‐, gender‐, and area‐matched controls from the International Collaborative Study of Cardiovascular Disease in Asia. Genotyping was performed using PCR‐RFLP. Logistic regression analyses revealed that carriers of the Gly16 allele… Expand
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