β-hydroxy-β-methylbutyrate did not enhance high intensity resistance training-induced improvements in myofiber dimensions and myogenic capacity in aged female rats.

@article{Kim2012hydroxymethylbutyrateDN,
  title={β-hydroxy-β-methylbutyrate did not enhance high intensity resistance training-induced improvements in myofiber dimensions and myogenic capacity in aged female rats.},
  author={Jeong-Su Kim and Y M Park and Sang-rok Lee and Ihssan S Masad and Andy V. Khamoui and Edward Jo and Bong-Sup Park and Bahram H Arjmandi and Lynn B. Panton and Won Jun Lee and Samuel C. Grant},
  journal={Molecules and cells},
  year={2012},
  volume={34 5},
  pages={439-48}
}
Older women exhibit blunted skeletal muscle hypertrophy following resistance training (RT) compared to other age and gender cohorts that is partially due to an impaired regenerative capacity. In the present study, we examined whether β-hydroxy-β-methylbutyrate (HMB) provision to aged female rodents would enhance regenerative mechanisms and facilitate RT-induced myofiber growth. Nineteen-month old female Sprague-Dawley rats were randomly divided into three groups: HMB (0.48 g/kg/d; n = 6), non… CONTINUE READING