β-cell autoimmunity in overweight non-diabetic youth: any implications?

@article{Libman2011cellAI,
  title={β-cell autoimmunity in overweight non-diabetic youth: any implications?},
  author={Ingrid M. Libman and Emma J. M. Barinas-Mitchell and Santica M. Marcovina and Fida Bacha and Tamara S. Hannon and Hala M Tfayli and So Jung Lee and Shelly Bansal and R. F. Robertson and Silva S Arslanian},
  journal={Pediatric diabetes},
  year={2011},
  volume={12 3 Pt 2},
  pages={207-11}
}
BACKGROUND AND OBJECTIVE The presence of β-cell antibodies is associated with a high risk of type 1 diabetes. With increasing rates of obesity, the distinction between obese T1DM and T2DM has become difficult. Moreover, increasing body mass index (BMI) in at-risk children has been proposed not only as a possible contributor to T1DM by increasing insulin resistance, but also as exerting an effect via the immunomodulatory properties of certain adipokines. This study aimed to determine prevalence… CONTINUE READING

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