β-catenin and Gli1 are prognostic markers in glioblastoma.

@article{Rossi2011cateninAG,
  title={β-catenin and Gli1 are prognostic markers in glioblastoma.},
  author={Marco Rossi and Letizia Magnoni and Clelia Miracco and Elisa Mori and P. Tosi and Luigi Pirtoli and Paolo Tini and Giuseppe Oliveri and Elena Cosci and Annette Bakker},
  journal={Cancer biology & therapy},
  year={2011},
  volume={11 8},
  pages={753-61}
}
Glioblastomas (GBMs), the most common primary malignancies of the central nervous system, are highly aggressive and heterogeneous, and remain a dramatic therapeutic challenge. Markers mirroring the complex molecular profile of GBMs that are predictive of patient outcomes are needed to define novel multi-targeted treatment strategies. Resistance to current GBM therapies is partly due to a subpopulation of stem-like and other self-renewing cells (hereafter called glioma stem-like cancer cells… CONTINUE READING

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