β-blockade restores muscle sympathetic rhythmicity in human heart failure.

Abstract

BACKGROUND Muscle sympathetic nerve firing rate increases as chronic heart failure (CHF) progresses, yet its oscillation, particularly within the frequency range encompassing 0.13 Hz, diminishes. The current study tested the hypothesis that chronic therapy with lipophilic β-adrenoceptor antagonists augments the modulation of muscle sympathetic nerve… (More)

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@article{Kubo2011blockadeRM, title={β-blockade restores muscle sympathetic rhythmicity in human heart failure.}, author={Toshihiko Kubo and Eduardo R. Azevedo and Gary E. Newton and Peter Picton and John D Parker and John S. Floras}, journal={Circulation journal : official journal of the Japanese Circulation Society}, year={2011}, volume={75 6}, pages={1400-8} }