β-Phenethyl isothiocyanate induces death receptor 5 to induce apoptosis in human oral cancer cells via p38.

@article{Huong2012PhenethylII,
  title={β-Phenethyl isothiocyanate induces death receptor 5 to induce apoptosis in human oral cancer cells via p38.},
  author={Le Diem Huong and J-A Shin and E-S Choi and N K Cho and H M Kim and D-H Leem and S Cho},
  journal={Oral diseases},
  year={2012},
  volume={18 5},
  pages={513-9}
}
OBJECTIVES β-Phenylethyl isothiocyanate (PEITC) has been demonstrated to fight many types of cancers through various molecular pathways. In this study, we focused on its effect on the induction of apoptosis to inhibit cell growth and molecular mechanism in oral cancer. MATERIALS AND METHODS 3-(4,5-dimethylthiazol-2-yl)-5-(2,4-disulfophenyl)-2-(4 sulfophenyl)-2H-tetrazolium (MTS) assay was used to examine cell viability. The apoptotic effect was investigated using 4'-6-Diamidino-2-phenylindole… CONTINUE READING
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