β-Glucans (Saccharomyces cereviseae) Reduce Glucose Levels and Attenuate Alveolar Bone Loss in Diabetic Rats with Periodontal Disease

@inproceedings{Silva2015GlucansC,
  title={β-Glucans (Saccharomyces cereviseae) Reduce Glucose Levels and Attenuate Alveolar Bone Loss in Diabetic Rats with Periodontal Disease},
  author={Viviam de Oliveira Silva and Raquel Vieira Lobato and Eric Francelino Andrade and Cristina Gomes de Macedo and Juliana Trindade Clemente Napimoga and Marcelo Henrique Napimoga and Michel R Messora and Ramiro Mendonça Murata and Luciano Jos{\'e} Pereira and {\"O}zlem Yilmaz},
  booktitle={PloS one},
  year={2015}
}
The objective of this study was to assess the effects of oral ingestion of β-glucans isolated from Saccharomyces cereviseae on the metabolic profile, expression of gingival inflammatory markers and amount of alveolar bone loss in diabetic rats with periodontal disease. Diabetes mellitus was induced in 48 Wistar rats by intraperitoneal injection of streptozotocin (80 mg/kg). After confirming the diabetes diagnosis, the animals were treated with β-glucans (by gavage) for 28 days. On the 14th day… CONTINUE READING
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