β-Escin sodium inhibits inducible nitric oxide synthase expression via downregulation of the JAK/STAT pathway in A549 cells.

@article{Ji2011EscinSI,
  title={β-Escin sodium inhibits inducible nitric oxide synthase expression via downregulation of the JAK/STAT pathway in A549 cells.},
  author={Deng Bo Ji and Bo Xu and Jing Liu and Fu Xiang Ran and Jing Rong Cui},
  journal={Molecular carcinogenesis},
  year={2011},
  volume={50 12},
  pages={945-60}
}
β-escin, a triterpene saponin, is one of the major active compounds extracted from horse chestnut (Aesculus hippocastanum) seed. Previous work has found that β-escin sodium has antiinflammatory and antitumor effects. In the present study, we investigated its effect on cell proliferation and inducible nitric-oxide synthase (iNOS) expression in human lung… CONTINUE READING