β-Elemene induces apoptosis in human renal-cell carcinoma 786-0 cells through inhibition of MAPK/ERK and PI3K/Akt/ mTOR signalling pathways.

@article{Zhan2012ElemeneIA,
  title={β-Elemene induces apoptosis in human renal-cell carcinoma 786-0 cells through inhibition of MAPK/ERK and PI3K/Akt/ mTOR signalling pathways.},
  author={Yun-Hong Zhan and Jing Liu and Xiujuan Qu and Ke-zuo Hou and Ke-Feng Wang and Yun-Peng Liu and Bin Wu},
  journal={Asian Pacific journal of cancer prevention : APJCP},
  year={2012},
  volume={13 6},
  pages={2739-44}
}
BACKGROUND Renal-cell carcinoma (RCC) is resistant to almost all chemotherapeutics and radiation therapy. β-Elemene, a promising anticancer drug extracted from a traditional Chinese medicine, has been shown to be effective against various tumors. In the present study, anti-tumor effects on RCC cells and the involved mechanisms were investigated. METHODS… CONTINUE READING