β-Blockade Treatment in Heart Failure: The Cardiac Insufficiency Bisoprolol Study (CIBIS) Project

@inproceedings{Lechat1990BlockadeTI,
  title={β-Blockade Treatment in Heart Failure: The Cardiac Insufficiency Bisoprolol Study (CIBIS) Project},
  author={Philippe Lechat},
  year={1990}
}
  • Philippe Lechat
  • Published 1990
  • Medicine
  • The efficacy of treatment with diuretics and vasodilators in heart failure has shown that compensatory mechanisms may induce vicious circles that can precipitate the deterioration of congestive heart failure (CHF). By counteracting sympathetic stimulation of cardiac β-receptors, β-blocing drugs could provide some benefit in CHF. Indeed, the sympathetic stimulation ehances metabolic costs and could lead to a further deterioration of myocardial fiber function. This could be counteracted by… CONTINUE READING

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