β-Arrestins Negatively Regulate the Toll Pathway in Shrimp by Preventing Dorsal Translocation and Inhibiting Dorsal Transcriptional Activity.

@article{Sun2016ArrestinsNR,
  title={β-Arrestins Negatively Regulate the Toll Pathway in Shrimp by Preventing Dorsal Translocation and Inhibiting Dorsal Transcriptional Activity.},
  author={Jie-Jie Sun and Jiangfeng Lan and Xiu-Zhen Shi and Ming-Chong Yang and Guo-Juan Niu and Ding Ding and Xiaofan Zhao and Xiao-qiang Yu and Jinxing Wang},
  journal={The Journal of biological chemistry},
  year={2016},
  volume={291 14},
  pages={7488-504}
}
The Toll signaling pathway plays an important role in the innate immunity ofDrosophila melanogasterand mammals. The activation and termination of Toll signaling are finely regulated in these animals. Although the primary components of the Toll pathway were identified in shrimp, the functions and regulation of the pathway are seldom studied. We first… CONTINUE READING