β-Adrenoceptor-mediated depolarization of the resting membrane in guinea-pig papillary muscles: changes in intracellular Na+, K+ and Cl− activities

Abstract

Effects of β-adrenergc stimulation on the membrane potential and intracellular Na+, K+ and Cl− activities were examined in isolated guinea-pig ventricular muscles using conventional and ion-selective elctrodes. Isoproterenol in concentrations of 30 nM−1 μM produced a transient depolarization followed by a slight hyperpolarization in electrically stimulated… (More)
DOI: 10.1007/BF00370698

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