β-Adrenergic receptors in guinea-pig myocardial tissue

@article{Krawietz2004AdrenergicRI,
  title={β-Adrenergic receptors in guinea-pig myocardial tissue},
  author={W. Krawietz and D. Poppert and Erland Erdmann and Hartmut H. Glossmann and Christine Struck and Christoph J Konrad},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={2004},
  volume={295},
  pages={215-224}
}
Stereospecific binding sites for (−) [3H]-alprenolol, a β-adrenergic antagonist, have been identified in guinea-pig myocardial broken cell preparations. The concentration of the sites was 0.3 pmoles per mg of protein and the dissociation constant (at 37°C) 10−8 M. A close correlation between the ability of various β-adrenergic antagonists to compete with… CONTINUE READING